Fluconazole vs. Nystatin prophylaxis for fungal infection in very low birth weight (VLBW) infants † 1486
نویسندگان
چکیده
منابع مشابه
Fluconazole prophylaxis against fungal colonization and invasive fungal infection in very low birth weight infants.
BACKGROUND Fungal infections are common cause of morbidity and mortality in very low birth weight Infants OBJECTIVES To evaluate the efficacy of prophylactic Fluconazole in preventing fungal colonization and invasive fungal infection in VLBW infants. DESIGN Prospective, randomized, double blind placebo controlled clinical trial. SETTING Tertiary level Neonatal intensive care unit. SUBJE...
متن کاملTargeted short-term fluconazole prophylaxis among very low birth weight and extremely low birth weight infants.
OBJECTIVES To assess whether targeted short-term fluconazole prophylaxis reduces late-onset (>3 days of age) invasive fungal infection (IFI) among very low birth weight infants and extremely low birth weight (ELBW) infants and to assess mortality rates, toxicity, and costs associated with this intervention. METHODS An observational study of 2 subsequent epochs of inborn infants with birth wei...
متن کاملEfficacy of Fluconazole Prophylaxis on Invasive Candidiasis Infection in Extremely Low Birth Weight Neonates
Background: Invasive candidiasis infection is one of the main life-threatening problems for extremely low birth weight (ELBW) neonates who are in the neonatal intensive care unit (NICU). Candidiasis can cause mortality, short-term morbidity, and long-term neurodevelopmental outcome in infected infants who survive. Therefore, since several years ago fluconazole prophylaxis has begun for prematur...
متن کاملRandomised controlled trial of prophylactic fluconazole versus nystatin for the prevention of fungal colonisation and invasive fungal infection in very low birth weight infants.
BACKGROUND Invasive fungal infections are a major cause of morbidity and mortality in preterm infants. The authors conducted the first prospective, randomised controlled trial of nystatin compared with fluconazole for the prevention of fungal colonisation and invasive fungal infection in very low birth weight (VLBW) neonates. METHODS During a 12-month period, all VLBW neonates were assigned r...
متن کاملFosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants
We conducted a retrospective case series study to evaluate the safety of fosfluconazole prophylaxis for preventing invasive fungal infection in VLBW infants with a central vascular access. Fosfluconazole was administered intravenously at a dose of 6 mg/kg everyday during which time a central venous catheter was placed. A total of 23 infants met the criteria for enrollment in our study. No cases...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-01507